Location: I-220 and US 49, Jackson Reassurance shield as US 49 joins I-220. Location: I-220 and US 49, Jackson Second reassurance shield after US 49 rejoins. Location: I-220 and Clinton Blvd, Jackson Reassurance shield after Clinton Blvd. Location: I-220 and Clinton Blvd, Jackson In a mile we’ll approach US 80. Location: I-220 and US 80, … Continue reading U.S. Route 49, I-220 to US-80